AUTHOR=Karthick Perumal , Mohanraju Raju 

TITLE=Antimicrobial Potential of Epiphytic Bacteria Associated With Seaweeds of Little Andaman, India

JOURNAL=Frontiers in Microbiology

VOLUME=9

YEAR=2018

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2018.00611

DOI=10.3389/fmicb.2018.00611

ISSN=1664-302X

ABSTRACT=<p>Seaweeds of the intertidal regions are a rich source of surface associated bacteria and are potential source of antimicrobial molecules. In the present study, 77 epiphytic isolates from eight different algae collected from Little Andaman were enumerated. On testing for their antimicrobial activities against certain pathogens twelve isolates showed positive and six of them showed significant antimicrobial inhibition zone against <italic>Shigella boydii</italic> type 1, <italic>Shigella flexneri</italic> type 2a, <italic>Shigella dysenteriae</italic> type 5, Enterotoxigenic <italic>Escherichia coli</italic> O115, Enteropathogenic <italic>E. coli</italic> serotype O114, <italic>Vibrio cholera</italic>; O1 Ogawa<italic>, Aeromonas hydrophila, Klebsiella pneumoniae, Staphylococcus aureus.</italic> Based on the activity these six isolates (G1C, G2C, G3C, UK, UVAD, and Tor1) were identified by 16S rRNA gene sequence and were found to belong to the phyla Firmicutes and Proteobacteria. Purified antimicrobial compounds obtained from these isolates were identified by GC-MS. Furan derivatives were identified from G2C <italic>Pseudomonas stutzeri</italic> KJ849834, UVAD <italic>Alcanivorax dieselolei</italic> KJ849833, UK <italic>Vibrio</italic> sp. KJ849837, Tor1 <italic>Exiguobacterium profundum</italic> KJ849838. While 2-Pyrrolidinone, Phenol, 2, 4-bis (1, 1-dimethylethyl) were from G3C <italic>Vibrio owensii</italic> KJ849836 and (1-Allylcyclopropyl) methanol from the extracts of G1C <italic>Bacillus</italic> sp. KJ849835. The results of the present study shows that these six potent isolates isolated from the seaweeds are found to be a source of antimicrobial compounds.</p>