AUTHOR=Heng Sing-Peng , Letchumanan Vengadesh , Deng Chuan-Yan , Ab Mutalib Nurul-Syakima , Khan Tahir M. , Chuah Lay-Hong , Chan Kok-Gan , Goh Bey-Hing , Pusparajah Priyia , Lee Learn-Han 

TITLE=Vibrio vulnificus: An Environmental and Clinical Burden

JOURNAL=Frontiers in Microbiology

VOLUME=8

YEAR=2017

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2017.00997

DOI=10.3389/fmicb.2017.00997

ISSN=1664-302X

ABSTRACT=<p><italic>Vibrio vulnificus</italic> is a Gram negative, rod shaped bacterium that belongs to the family <italic>Vibrionaceae</italic>. It is a deadly, opportunistic human pathogen which is responsible for the majority of seafood-associated deaths worldwide. <italic>V. vulnificus</italic> infection can be fatal as it may cause severe wound infections potentially requiring amputation or lead to sepsis in susceptible individuals. Treatment is increasingly challenging as <italic>V. vulnificus</italic> has begun to develop resistance against certain antibiotics due to their indiscriminate use. This article aims to provide insight into the antibiotic resistance of <italic>V. vulnificus</italic> in different parts of the world as well as an overall review of its clinical manifestations, treatment, and prevention. Understanding the organism's antibiotic resistance profile is vital in order to select appropriate treatment and initiate appropriate prevention measures to treat and control <italic>V. vulnificus</italic> infections, which should eventually help lower the mortality rate associated with this pathogen worldwide.</p>