AUTHOR=Zhao Ying , Bi Kai , Gao Zhixiao , Chen Tao , Liu Huiquan , Xie Jiatao , Cheng Jiasen , Fu Yanping , Jiang Daohong 

TITLE=Transcriptome Analysis of Arabidopsis thaliana in Response to Plasmodiophora brassicae during Early Infection

JOURNAL=Frontiers in Microbiology

VOLUME=8

YEAR=2017

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2017.00673

DOI=10.3389/fmicb.2017.00673

ISSN=1664-302X

ABSTRACT=<p>Clubroot disease is a serious threat to cruciferous plants worldwide, especially to oilseed rape. However, knowledge on pathogenic molecular mechanisms and host interaction is limited. We presume that the recognition between <italic>Arabidopsis thaliana</italic> and <italic>Plasmodiophora brassicae</italic> occurs at the early stage of infection and within a relatively short period. In this study, we demonstrated changes on gene expression and pathways in <italic>A. thaliana</italic> during early infection with <italic>P. brassicae</italic> using transcriptome analysis. We identified 1,903 and 1,359 DEGs at 24 and 48 h post-inoculation (hpi), respectively. Flavonoids and the lignin synthesis pathways were enhanced, glucosinolates, terpenoids, and proanthocyanidins accumulated and many hormonal- and receptor-kinase related genes were expressed, caused by <italic>P. brassicae</italic> infection during its early phase. Therefore, the early interaction between <italic>A. thaliana</italic> and <italic>P. brassicae</italic> plays an important role in the entire infection process. The results provide a new contribution to a better understanding of the interaction between host plants and <italic>P. brassicae</italic>, as well as the development of future measures for the prevention of clubroot.</p>