AUTHOR=Malwade Akshay , Nguyen Angel , Sadat-Mousavi Peivand , Ingalls Brian P. TITLE=Predictive Modeling of a Batch Filter Mating Process JOURNAL=Frontiers in Microbiology VOLUME=8 YEAR=2017 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2017.00461 DOI=10.3389/fmicb.2017.00461 ISSN=1664-302X ABSTRACT=
Quantitative characterizations of horizontal gene transfer are needed to accurately describe gene transfer processes in natural and engineered systems. A number of approaches to the quantitative description of plasmid conjugation have appeared in the literature. In this study, we seek to extend that work, motivated by the question of whether a mathematical model can accurately predict growth and conjugation dynamics in a batch process. We used flow cytometry to make time-point observations of a filter-associated mating between two