AUTHOR=Wong Marcus H. , Xie Miaomiao , Xie Liqi , Lin Dachuan , Li Ruichao , Zhou Yuanjie , Chan Edward W. , Chen Sheng 

TITLE=Complete Sequence of a F33:A-:B- Conjugative Plasmid Carrying the oqxAB, fosA3, and blaCTX-M-55 Elements from a Foodborne Escherichia coli Strain

JOURNAL=Frontiers in Microbiology

VOLUME=7

YEAR=2016

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2016.01729

DOI=10.3389/fmicb.2016.01729

ISSN=1664-302X

ABSTRACT=<p>This study reports the complete sequence of pE80, a conjugative IncFII plasmid recovered from an <italic>Escherichia coli</italic> strain isolated from chicken meat. This plasmid harbors multiple resistance determinants including <italic>oqxAB</italic>, <italic>fosA3</italic>, <italic>bla</italic><sub>CTX-M-55,</sub> and <italic>bla</italic><sub>TEM-1</sub>, and is a close variant of the recently reported p42-2 element, which was recovered from <italic>E. coli</italic> of veterinary source. Recovery of pE80 constitutes evidence that evolution or genetic re-arrangement of IncFII type plasmids residing in animal-borne organisms is an active event, which involves acquisition and integration of foreign resistance elements into the plasmid backbone. Dissemination of these plasmids may further compromise the effectiveness of current antimicrobial strategies.</p>