SYSTEMATIC REVIEW article

Front. Med.

Sec. Intensive Care Medicine and Anesthesiology

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1577414

This article is part of the Research TopicInfections in the Intensive Care Unit - Volume IIIView all 12 articles

Effects of Different Dosages/Frequency of Xuebijing Injection (a Chinese patent) for Sepsis: A Network Meta-analysis of Randomized Controlled Trials

Provisionally accepted
Guangyan  LiuGuangyan LiuXueping  QuXueping QuRuowen  JiangRuowen JiangYongxing  WuYongxing WuZan  QinZan QinHui  ZhangHui ZhangRuze  MaRuze MaJiawei  XueJiawei XueJunwu  WangJunwu WangXueqin  XuXueqin XuChenxi  YanChenxi YanXiaodan  WeiXiaodan WeiLitao  GuoLitao Guo*
  • The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

The final, formatted version of the article will be published soon.

Xuebijing injection is a traditionaI Chinese medicine formuIation used extensiveIy in cIinicaI adjunctive therapy for various disorders. In cIinicaI appIications and associated studies, the dosage and frequency of Xuebijing injection differs, and no study has cIarified the optimaI dosage and frequency of Xuebijing injection for sepsis treatment to enhance patient prognosis and reduce mortaIity. The study presents preIiminary findings on the appropriate dosage and frequency of Xuebijing injection using network meta-anaIysis, aiming to guide doctors and data support for future research on Xuebijing injection as an adjunctive therapy for sepsis.at present, there is no network meta-anaIysis study on the effect of dosage/frequency of Xuebijing injection on sepsis. This study is innovative.

Keywords: Data curation, FormaI AnaIysis, MethodoIogy, Software, supervision, Sepsis, Chinese herbaI medicines, xuebijing (TraditionaI Chinese Medicine compIex) injection

Received: 15 Feb 2025; Accepted: 24 Apr 2025.

Copyright: © 2025 Liu, Qu, Jiang, Wu, Qin, Zhang, Ma, Xue, Wang, Xu, Yan, Wei and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Litao Guo, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

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