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CASE REPORT article
Front. Med.
Sec. Gastroenterology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1577291
Epigastric Pain of Unknown Origin, Esophageal and Gastric Involvement: A Henoch-Schönlein Purpura Case Report
Provisionally accepted
Mengmeng Li 1
Chaoyuan Huang 2 Hailun Xing 2 Shijuan Luo 2 Yiqun Lin 2 Yuxiang Kuang 2 Jing Wang 2 Suiping Huang 2 Zhenhao Ye 2*- 1 Guangzhou University of Chinese Medicine, Guangzhou, China
- 2 Department of Gastroenterology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong Province, China
Henoch-Schönlein Purpura (HSP) is an acute systemic vasculitis that primarily affects the skin, gastrointestinal tract, kidneys and joints. It predominantly occurs in children but can occur at any age. We report a case of 48-year-old male patient suffering from unexplained epigastric pain alternating between relapses and remissions. The patient's initial clinical manifestation was atypical, starting with severe epigastric pain, without cutaneous purpura, and with normal rheumatologic and immunologic markers, making diagnosis difficult. The patient was eventually diagnosed with HSP. This case highlights the importance of considering this diagnosis in patients with unexplained abdominal pain and emphasize the role of endoscopy in diagnosing complex cases.
Keywords: Henoch-Schönlein purpura, Intramural hematoma of the esophagus, Gastric Mucosal Erythema, Abdominal Pain, Epigastric pain
Received: 07 Mar 2025; Accepted: 01 Apr 2025.
Copyright: © 2025 Li, Huang, Xing, Luo, Lin, Kuang, Wang, Huang and Ye. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zhenhao Ye, Department of Gastroenterology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510000, Guangdong Province, China
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