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MINI REVIEW article
Front. Med.
Sec. Dermatology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1574697
This article is part of the Research Topic Advancing Atopic Dermatitis Management: Translational Research and Emerging Therapies View all 4 articles
Enabling precision medicine with biomarkers of response to treatment in atopic dermatitis: where are we now? A narrative review
Provisionally accepted
medical writer medical writer 1
Andrea Chiricozzi 2,3
Anna Levi 4
Chiara Palladino 4
Giampiero Girolomoni 5*- 1 astw, genova, Italy
- 2 Unit of Dermatology, Department of Medical and Surgical Sciences, Agostino Gemelli University Polyclinic (IRCCS), Rome, Lazio, Italy
- 3 Departments of Medicine and Translational Surgery, Catholic University of the Sacred Heart, Rome, Rome, Lazio, Italy
- 4 AbbVie (Italy), Rome, Lazio, Italy
- 5 Department of Medicine, Verona University Hospital, Verona, Veneto, Italy
Atopic dermatitis (AD) is a complex systemic disease characterized by high heterogeneity both at clinical and pathophysiology levels. While advances in drug development towards a more targeted approach are made, treatment and management of AD patients are still happening according to the one-size-fits-all approach. To enhance precision medicine in AD and improve care, identifying predicting factors of response to therapy driving tailored treatments will be of utmost importance. Here, we discuss the available evidence regarding predictive biomarkers, as well as their possible and still debated impact in clinical practice.
Keywords: atopic dermatitis, targeted therapies, predictive biomarkers, precision medicine, Personalized approach
Received: 11 Feb 2025; Accepted: 28 Mar 2025.
Copyright: © 2025 medical writer, Chiricozzi, Levi, Palladino and Girolomoni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Giampiero Girolomoni, Department of Medicine, Verona University Hospital, Verona, 37134, Veneto, Italy
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.