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ORIGINAL RESEARCH article
Front. Med.
Sec. Family Medicine and Primary Care
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1572261
This article is part of the Research Topic Nutraceutical Formulations and Natural Compounds for the Management of Chronic Diseases View all articles
Open Label Study of a Novel Fiber Product for Bloating, Gas and Bowel Regularity
Provisionally accepted- 1 Biology Department, Southern Methodist University, Dallas, North Carolina, United States
- 2 Indiana University, Bloomington, Indiana, United States
- 3 LX Medical, Edina, United States
AbstractIntroduction: This open-label study evaluated the effects of a novel fiber supplement product, Relievance, on bowel movement regularity and symptoms of bloating and gas in 20 consecutive patients. The product is a commercially available combination of 8 natural fibers and the recommended dose is 4-5 grams per serving. Methods: Participants, presenting with chronic bothersome gastrointestinal symptoms of bloating, gas or bowel irregularity were recruited from an outpatient primary care practice for the study. Participants consumed 4-5 g of the fiber blend (one heaping teaspoon), one to three times per day, over six weeks, and kept diaries on symptoms and number of bowel movements per week. Symptoms were assessed via a 6-point analog scale at baseline and at 6 weeks. Primary endpoints included changes in bowel movement frequency and symptom severity related to gas and bloating. Results: At baseline, participants averaged 1.7 bowel movements per week, which significantly increased to 3.2 per week by the study's conclusion. Symptom severity scores for bloating and gas also improved significantly, decreasing from 3.0 at baseline to 1.5 after six weeks. These results demonstrated statistically significant improvements in both bowel regularity and symptom relief. No significant adverse events were reported during the study, highlighting the product's safety profile. Conclusion: This small, non-randomized prospective trial suggests that Relievance, a proprietary blend of eight different fibers, may effectively enhance bowel movement frequency and alleviate symptoms of bloating and gas. Further randomized controlled trials are warranted to confirm these findings and explore broader applications.
Keywords: Gas, Bloating, Fiber, Constipation, Flatulence
Received: 06 Feb 2025; Accepted: 26 Feb 2025.
Copyright: © 2025 Ganz, Greeley, Riggen and Riggen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Alexander S. Ganz, Biology Department, Southern Methodist University, Dallas, 75275, North Carolina, United States
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