Corrigendum: Progesterone, cerclage, pessary, or acetylsalicylic acid for prevention of preterm birth in singleton and multifetal pregnancies -A systematic review and meta-analyses

Ulla-Britt Wennerholm ^* Lina Bergman Bo Jacobsson Annika Strandell

• Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

In the published article, there was an error. "[This concerns the results of the meta-analyses, which have marginally changed after exclusion of an article that has been retracted and was included in several meta-analyses: Cetingoz E et al. Progesterone effects on preterm birth in high-risk pregnancies: a randomized placebo-controlled trial. Arch Gynecol Obstet. 2011 Mar;283(3):423-9. We observed a retraction note for this article that was published in: Arch Gynecol Obstet. 2024 Sep;310(3):1777. The scientific conclusions of our systematic review will not be changed.]" This sentence previously stated: "[Low risk of bias trials showed an overall effect of progesterone to reduce the risk of preterm birth (Table 2 and Figure 2A). A reduction of any preterm birth was demonstrated for <37 gestational weeks (26.8% vs. 30.2%, RR 0.82; 95% CI 0.71 to 0.95) and <34 gestational weeks (11.7% vs. 15.2%, RR 0.78; 95% CI 0.68 to 0.89) for any administration route (high certainty of evidence).]"The corrected sentence appears below: "[Low risk of bias trials showed an overall effect of progesterone to reduce the risk of preterm birth (Table 2 andFigure 2A). A reduction of any preterm birth was demonstrated for <37 gestational weeks (26.7% vs. 30.3%, RR 0.82; 95% CI 0.71 to 0.96) and <34 gestational weeks (11.8% vs. 15.4%, RR 0.78; 95% CI 0.67 to 0.89) for any administration route (high certainty of evidence).]" A correction has been made to [Results], [Progesterone, Preterm birth across gestational weeks in multifetal pregnancies]. This sentence previously stated: "[Low risk of bias trials demonstrated no effect of progesterone (any administration route) on the risk of any preterm birth <37 gestational weeks (58.3% vs. 57.2%, RR 1.01; 95% CI 0.95 to 1.08) (moderate certainty of evidence), and <34 gestational weeks (22.4% vs. 21.6%, RR 1.02; 95% CI 0.92 to 1.12) (high certainty of evidence), neither on < 35, <32, <28 gestational weeks (high certainty of evidence), nor on the risk of spontaneous preterm birth (low to moderate certainty of evidence)]."The corrected sentence appears below: "[Low risk of bias trials demonstrated no effect of progesterone (any administration route) on the risk of any preterm birth <37 gestational weeks (58.5% vs. 56.6%, RR 1.03; 95% CI 0.97 to 1.08) (moderate certainty of evidence), and <34 gestational weeks (22.8% vs. 21.5%, RR 1.02; 95% CI 0.93 to 1.13) (high certainty of evidence), neither on < 35, <32, <28 gestational weeks (high certainty of evidence), nor on the risk of spontaneous preterm birth (low to moderate certainty of evidence)]."The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.