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ORIGINAL RESEARCH article
Front. Med.
Sec. Obstetrics and Gynecology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1555256
Reproductive outcomes after TCRS in patients with incomplete and complete uterine septum: A retrospective cohort study
Provisionally accepted
JIAN YANG 1
Cong-Qing Li 1
Jingxian XIA 2
Zhu Wenjing 1 Jing Wang 3 Wei He 1 Qing-Yuan Wang 1 Wen-Yan Wang 1*- 1 Second Hospital of Anhui Medical University, Hefei, China
- 2 Fuyang Women's and Children's Hospital, Fuyang, Jiangsu Province, China
- 3 Anhui Maternal and Child Health Hospital, Hefei, Anhui Province, China
Objective: To evaluate the effects of transcervical resection of the septum (TCRS) for two kinds of uterine septum on reproductive outcomes among women of reproductive age.Methods: In this retrospective cohort study, we evaluated the reproductive outcomes after TCRS of 87 women with incomplete uterine septum and 35 women with complete uterine septum from January 2010 to December 2020 at the Second Affiliated Hospital of Anhui Medical University in China.Results: Results: In Group A (Incomplete uterine septum), TCRS markedly decreased the rates of spontaneous abortion and embryo arrest (P<0.001), while significantly enhancing the likelihood of term delivery (P<0.001). Similarly, Group B (Complete uterine septum) observed a substantial increase in pregnancy rates (from 43.5% to 82.6%), a significant decrease in spontaneous abortions (P<0.05), and an improvement in term delivery rates (P<0.001) post-surgery. The dimension of the septum in cases of Group A did not affect the outcome of adverse reproductive events. However, cesarean section rates were significantly higher in Group B than in Group A (76.5% vs. 47.7%).The optimum time for achieving pregnancy was within the first year for Group A and the 12th month for Group B after TCRS.In patients undergoing TCRS, a notable decrease in spontaneous abortion rates was observed, alongside an increase in pregnancy and full-term birth rates.However, there was a concomitant rise in cesarean section rates. Furthermore, our findings indicate that patients with an incomplete uterine septum are more likely to conceive earlier than those with a complete uterine septum following surgery, thereby optimizing the timing for pregnancy.
Keywords: Uterine septum, complication, delivery, optimum gestation time, Reproductive outcome
Received: 04 Jan 2025; Accepted: 04 Apr 2025.
Copyright: © 2025 YANG, Li, XIA, Wenjing, Wang, He, Wang and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Wen-Yan Wang, Second Hospital of Anhui Medical University, Hefei, China
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