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ORIGINAL RESEARCH article
Front. Med.
Sec. Pulmonary Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1554723
Impact of Vitamin C Deficiency on Imaging Patterns and Ventilatory Function in Pulmonary Tuberculosis
Provisionally accepted
RAMONA CIOBOATA1
Mara Amalia BĂLTEANU2
Ovidiu Mircea Zlatian3*
Silviu Gabriel Vlasceanu4*
Mircea Driga Popescu3
Denisa Maria Mitroi5
Oana Maria Catana5
Cezar Ionut Buciu5
Georgiana Camen6Adina Andreea Mirea7- 1Pneumology Department, University of Medicine and Pharmacy of Craiova, Craiova, Romania
- 2Department of Pulmonology, Faculty of Medicine, Titu Maiorescu University, Craiova, Romania
- 3Microbiology Department, University of Medicine and Pharmacy of Craiova, CRAIOVA, Romania
- 4Physiology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
- 5Doctoral School, University of Medicine and Pharmacy of Craiova, Craiova, Romania
- 6Radiology Department, University of Medicine and Pharmacy of Craiova, Craiova, Romania
- 7Department of Oral-Dental Prevention University of Medicine and Pharmacy of Craiova, CRAIOVA, Romania
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Background: Studies have shown that vitamin C is essential for the immune response to tuberculosis (TB),TB and that its deficiency may elevate the risk of TB and related complications. This prospective study investigated the association between disease severity, imaging findings and vitamin C levels.Mycobacterium tuberculosis cultureby culture of Mycobacterium tuberculosis. Patients were divided into two groups based on serum vitamin C levels: 59 patients (54.13%) with normal levels and 50 (45.87%) with low levels.
Keywords: pulmonary tuberculosis, Spirometry, vitamin C, Chest imaging, CT scan
Received: 02 Jan 2025; Accepted: 14 Apr 2025.
Copyright: © 2025 CIOBOATA, BĂLTEANU, Zlatian, Vlasceanu, Popescu, Mitroi, Catana, Buciu, Camen and Mirea. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ovidiu Mircea Zlatian, Microbiology Department, University of Medicine and Pharmacy of Craiova, CRAIOVA, Romania
Silviu Gabriel Vlasceanu, Physiology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.