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ORIGINAL RESEARCH article

Front. Med.

Sec. Ophthalmology

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1551315

This article is part of the Research Topic Efficient Artificial Intelligence in Ophthalmic Imaging – Volume II View all 4 articles

A Lightweight Multi-Deep Learning Framework for Accurate Diabetic Retinopathy Detection and Multi-Level Severity Identification

Provisionally accepted
  • 1 Sejong University, Seoul, Republic of Korea
  • 2 Pukyong National University, Busan, Republic of Korea
  • 3 Pusan National University, Busan, Busan, Republic of Korea

The final, formatted version of the article will be published soon.

    Accurate and timely detection of diabetic retinopathy (DR) is crucial for managing its progression and improving patient outcomes. However, developing algorithms to analyze complex fundus images continues to be a major challenge. This work presents a lightweight deep-learning network developed for DR detection. The proposed framework consists of two stages. In the first step, the developed model is used to assess the presence of DR (i.e., healthy (No DR) or diseased (DR)). The next step involves the use of transfer learning for further subclassification of DR severity (i.e., mild, moderate, severe DR, and proliferative DR). The designed model is reused for transfer learning, as correlated images facilitate further classification of DR severity. The online dataset is used to validate the proposed framework, and results show that the proposed model is lightweight and has comparatively low learnable parameters compared to others. The proposed two-stage framework enhances the classification performance, achieving a 99.06% classification rate for DR detection and an accuracy of 90.75% for DR severity identification for APTOS 2019 dataset.

    Keywords: Diabetic Retinopathy, Fundus imaging, Deep learning model, Lightweight model, Transfer Learning

    Received: 25 Dec 2024; Accepted: 10 Mar 2025.

    Copyright: © 2025 Zafar, Kim, Ali, Byun and Kim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Seong-Han Kim, Sejong University, Seoul, Republic of Korea

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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