Skip to main content

CASE REPORT article

Front. Med.

Sec. Pulmonary Medicine

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1545428

Occupational Methanol Toxicity: A Case Report

Provisionally accepted
  • 1 Ministry of Health (Saudi Arabia), Riyadh, Riyadh, Saudi Arabia
  • 2 Zagazig University, Zagazig, Egypt

The final, formatted version of the article will be published soon.

    This case report describes a case of methanol occupational toxicity in a 44-year-old male ship worker following in Jeddah, Saudi Arabia, on August 27, 2024. The patient suddenly lost sight in both eyes and had an unusual acid-base disturbance that was marked by respiratory alkalosis (pH 7.607). This is different from the acidosis that is usually seen in methanol poisoning. Despite aggressive treatment with FOMEPIZOLE, the methanol antidote, and 4 hemodialysis sessions, the patient's visual prognosis remained poor. This case highlights the potentially devastating consequences of inhalational and contact methanol poisoning and the importance of prompt recognition and treatment, even in the absence of significant neuroimaging findings. It also underscores the need for proper use of personal protective equipment (PPE) in the workplace.

    Keywords: methanol toxicity, Inhalation, Vision Loss, Metabolic alkalosis, optic neuropathy.

    Received: 18 Dec 2024; Accepted: 21 Mar 2025.

    Copyright: © 2025 Alrougi, Saqah, Khojah and Amer. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Hamoud M Alrougi, Ministry of Health (Saudi Arabia), Riyadh, 11176, Riyadh, Saudi Arabia
    Samar Ahmed Amer, Zagazig University, Zagazig, Egypt

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

    Research integrity at Frontiers

    Man ultramarathon runner in the mountains he trains at sunset

    95% of researchers rate our articles as excellent or good

    Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


    Find out more