CASE REPORT article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1544319
Kyrieleis plaques in an unusual Behcet's disease uveitis
Provisionally accepted
- Department of Ophthalmology, Second Xiangya Hospital, Central South University, Changsha, China
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Kyrieleis plaques are a rare retinal manifestation and have been seldom reported in Behcet's disease uveitis. We report the case of a 41-year-old male who presented with Behçet's disease uveitis combined with central serous chorioretinopathy. Laboratory studies showed positive for human leukocyte antigen B51. Polymerase chain reaction analysis of aqueous humor excluded infectious uveitis. Kyrieleis plaques were observed in the bilateral retinal arteries. These plaques persisted in both eyes after half a year of immunosuppressive treatments. The presence of Kyrieleis plaques is not exclusive to infectious uveitis and can also be associated with Behçet's disease uveitis.
Keywords: Behcet's disease, Kyrieleis plaques, Central Serous Chorioretinopathy, Uveitis, Adalimumab
Received: 12 Dec 2024; Accepted: 17 Apr 2025.
Copyright: © 2025 Li, Zhao, Guo and Xiao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yangyan Xiao, Department of Ophthalmology, Second Xiangya Hospital, Central South University, Changsha, China
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