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SYSTEMATIC REVIEW article

Front. Med.
Sec. Geriatric Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1537240
This article is part of the Research Topic Frailty- and Age-Associated Diseases: Possibilities For Intervention (Volume 2) View all 5 articles

The association between cognitive frailty and the risk of fall occurrence in older adults：A meta-analysis of cohort studies

Provisionally accepted
Jian Liu Jian Liu Yu Wu Yu Wu Zongke Long Zongke Long *Simeng Zhang Simeng Zhang *Shicai Wu Shicai Wu *
  • Shandong University, Jinan, China

The final, formatted version of the article will be published soon.

    AbstractBackground: Cognitive frailty increases the risk of fall occurrence. However, previous studies have shown inconsistent correlations between cognitive frailty and the risk of fall occurrence.Objective: To systematically review studies and explore the association between cognitive frailty and the risk of fall occurrence. Methods: Databases were systematically searched. Meta-analysis was performed using RevMan 5.4 software after evaluation of the quality of the included studies by 2 researchers.Results: A total of five studies including 16,962 patients were included. The results of Meta-analysis showed that the cognitive frailty group increased the risk of occurrence of falls in older adults [OR=1.38,95%CI (1.09,1.73), P=0.006]. Subgroup analyses showed that cognitive frailty in older adults increased the risk of fall occurrence using different cognitive frailty assessment tools, study participants from the community, different regions, and different sample sizes. Conclusions: The results of this study suggest that cognitive frailty in older adults is an independent risk factor for the occurrence of falls, and it is recommended that caregivers strengthen the assessment of cognitive aspects of older adults admitted to the hospital.

    Keywords: cognitive frailty, falls, Meta-analysis, older adults, Systematic review

    Received: 30 Nov 2024; Accepted: 30 Jan 2025.

    Copyright: © 2025 Liu, Wu, Long, Zhang and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Zongke Long, Shandong University, Jinan, China
    Simeng Zhang, Shandong University, Jinan, China
    Shicai Wu, Shandong University, Jinan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.