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SYSTEMATIC REVIEW article
Front. Med.
Sec. Gastroenterology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1530835
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1) Background: Gastric ulcers are a form of peptic ulcers that present as ruptures of the mucosal lining of the stomach or the proximal intestinal lining extending beyond the muscularis mucosae, and Helicobacter pylori infection is one of the main causative factors of gastric ulcers. However, the growing incidence of Helicobacter pylori drug resistance and the emergence of specialised ulcers has necessitated continued research on gastric ulcers. This study surveyed global gastric ulcer research over the past two decades with the aim of identifying the major findings and emerging trends in the field. (2) Methods: Bibliometric analysis was performed using the search terms 'Gastric ulcer', 'Gastric ulcer disease', 'Gastrohelcoma', and 'Stomach ulcers'. Data were extracted from the Web of Science Core Database (WoSCC) and visualised using CiteSpace software. (3) Results: The Journal of Gastroenterology had the most cited papers. The largest number of papers was from the United States. The most frequently cited keywords were 'Helicobacter pylori', 'peptic ulcer', and 'gastric ulcer'. (4) Conclusions: The field of gastric ulcer research is rapidly expanding, and the existing research is focused on preventing the occurrence of gastric ulcers, exploring the pathogenesis of gastric ulcers, and identifying new methods of treating gastric ulcers.
Keywords: Gastric ulcer1, Stomach ulcers2, Helicobacter pylori3, Marginal ulcer4, antioxidant5, Gut microbiota6, Antibiotic resistance7
Received: 26 Nov 2024; Accepted: 10 Feb 2025.
Copyright: © 2025 Liu, Li, Liu, Sun, Song, Lu and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Dan Zhou, Changchun University of Chinese Medicine, Changchun, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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