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CASE REPORT article
Front. Med.
Sec. Hematology
Volume 12 - 2025 |
doi: 10.3389/fmed.2025.1528131
Hetrombopag Treatment for Immune Thrombocytopenia in Pregnancy Refractory to Corticosteroids and Intravenous Immunoglobulin: A Case Report
Provisionally accepted- Department of Hematology, Affiliated Haikou Hospital Xiangya School Central South University and Haikou Municipal Municipal People’s Hospital, Haikou, China
Pregnancy can lead to the recurrence or exacerbation of immune thrombocytopenia (ITP).Currently, first-line treatments of low-dose corticosteroids or intravenous immunoglobulin are considered safe and effective for both pregnant women and fetuses. However, there is no well-established treatment option for patients who are refractory to these medications. Herein, we report a case of a 31-year-old pregnant woman with recurrent and refractory ITP who was safely and effectively treated with hetrombopag, with no influence on the infant's platelet count. This case explores a new treatment option for the management of recurrent and refractory ITP in pregnancy.
Keywords: Pregnancy, immune thrombocytopenia, Hetrombopag, Recombinant human thrombopoietin, case report
Received: 14 Nov 2024; Accepted: 27 Jan 2025.
Copyright: © 2025 Pang, Yu and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaoyang Yang, Department of Hematology, Affiliated Haikou Hospital Xiangya School Central South University and Haikou Municipal Municipal People’s Hospital, Haikou, China
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