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CASE REPORT article
Front. Med.
Sec. Pulmonary Medicine
Volume 12 - 2025 |
doi: 10.3389/fmed.2025.1515233
This article is part of the Research Topic Advancements in Multimodal Data Analysis for Lung Tumor Diagnosis View all 11 articles
Primary Cardiac Synovial Sarcoma with Suspected Connective Tissue Disease Diagnosed by EBUS-TBMB
Provisionally accepted- 1 Chongqing Emergency Medical Center, Chongqing, China
- 2 First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing Municipality, China
- 3 Shanghai Children's Hospital, Shanghai, Shanghai Municipality, China
Primary cardiac synovial sarcoma (PCSS), which most commonly originates in the right atrium of the heart, is exceptionally rare. Although biomarkers of autoimmune diseases such as antinuclear antibodies (ANAs) have been reported to be potential indicators of certain tumors, the association between PCSS and ANAs remains unclear.Herein, we describe a case presenting with pleural effusion considered to be connective tissue disease (CTD) and finally diagnosed with PCSS by endobronchial-ultrasound guided transbronchial mediastinum biopsy (EBUS-TBMB). Clinicians need to update their knowledge regarding the potential association of PCSS with ANAs. This case report also emphasizes the importance of EBUS-TBMB under the guidance of PET/CT in the diagnosis of this rare tumor with an unusual location.
Keywords: Primary cardiac synovial sarcoma, Antinuclear Antibodies, Pleural Effusion, Connective tissue disease, EBUS-TBMB
Received: 22 Oct 2024; Accepted: 20 Jan 2025.
Copyright: © 2025 Feng, Wu, Chi, Li, Wang and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Rui Guo, First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, Chongqing Municipality, China
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