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SYSTEMATIC REVIEW article

Front. Med.

Sec. Obstetrics and Gynecology

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1513213

This article is part of the Research Topic Pioneers & Pathfinders: 10 Years of Frontiers in Medicine View all 12 articles

Global research of NK cells in miscarriage: a bibliometric study

Provisionally accepted
Jinli Ding Jinli Ding *Chaogang Yang Chaogang Yang Yinan Wang Yinan Wang Xiaoqin He Xiaoqin He
  • Renmin Hospital of Wuhan University, Wuhan, China

The final, formatted version of the article will be published soon.

    The aim of this study was to assess the evolution, trends and research hotspots of publications related to Natural killer (NK) cells and miscarriage.: The literature on NK cells and miscarriage was retrieved from the Web of Science Core Collection. VOSviewer and CiteSpace were used to analyze THE publication years, countries, institutions, journals, highly cited authors, categories and citation bursts of keywords. Results: A total of 1,275 articles were analyzed. The annual publication outputs showed steady growth, with the most publications in 2020 and citations in 2022. The number of publications in this field raised in fluctuation from 1981 until 2023 with a slight downward trend observed, while the number of citations increased steadily until 2023, followed by a minor decline. The United States contributed highest number of publications and had the highest H-index. The American Journal of Reproductive Immunology ranked first in terms of number of publications and H-index. Reproductive biology, immunology, and obstetrics gynecology were the most representative disciplines. Kwak-kim J, Chaouat G and Croy BA were the top three most productive authors in the field. Keyword burst analysis demonstrated that immune system and cytotoxicity receptors were current research hotspots. Conclusions: This is the first bibliometric study to comprehensively summarize trends and advances in the study of NK cells in miscarriage. These information demonstrate the recent research frontiers and hot directions, and provide a reference for subsequent research in the future.

    Keywords: bibliometric analysis, NK cells, miscarriage, Citespace, VOSviewer

    Received: 18 Oct 2024; Accepted: 27 Jan 2025.

    Copyright: © 2025 Ding, Yang, Wang and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jinli Ding, Renmin Hospital of Wuhan University, Wuhan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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