SYSTEMATIC REVIEW article
Front. Med.
Sec. Pulmonary Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1512729
Efficacy and Safety of Traditional Chinese Medicine in the Treatment of Chronic Pulmonary Diseases: A Systematic Review and Meta-Analysis
Provisionally accepted
Hong-Yan Cai1*
Shan An2- 1The first Clinical Hospital of Jilin Academy of Traditional Chinese medicine, Changchun, China
- 2Changchun University of Chinese Medicine, Changchun, Jilin Province, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background: To assess the efficacy and safety of various TCMIs treatments for COPD using network meta-analysis, providing evidence and guidance for clinical practice.Methods: We will search 7 databases for randomized controlled trials of TCMI for the COPD, including PubMed, the Cochrane Library, EMbase, China National Knowledge Infrastructure, China Biological Medicine, Chinese Scientific Journals Database,and Wan-fang databases, from the date of the establishment of each database to October 31, 2021. The network meta-analysis will be implemented through Aggregate Data Drug Information System 1.16.8 and Stata13.0 software. Pulmonary function included forced expiratory volume in 1 second (FEV1),forced vital capacity (FVC), and FEV1/FVC will be the primary outcomes,FEV1 as a percentage of the estimated value, maximal voluntary ventilation (MVV), MVV as a percentage of the estimated value, 6 minutes walking distance, The St. Results: A total of seven appropriate studies were identified, encompassing 490 patients. The quality of the literature was satisfactory, with no significant publication bias detected. The effectiveness rate for patients receiving a combination of TCM and Western Medicine (WM) compared to those on WM alone was evaluated as an odds ratio (OR) , with statistical testing yielding Z=6.09. For PO2 levels post-treatment, the mean difference (MD) was reported as 5.92.
Keywords: chronic obstructive pulmonary disease, COPD, Injections, Network meta-analysis, protocol, Systematic review, Traditional Chinese Medicine
Received: 17 Oct 2024; Accepted: 18 Apr 2025.
Copyright: © 2025 Cai and An. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Hong-Yan Cai, The first Clinical Hospital of Jilin Academy of Traditional Chinese medicine, Changchun, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.