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CASE REPORT article
Front. Med.
Sec. Nephrology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1509018
Case report ： Gouty renal abscess and gouty sacroiliitis associated with genetic variants of a young woman
Provisionally accepted- 1 The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China
- 2 The Department of Rheumatology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen ，Guangdong, China
Gout is a form of inflammatory arthritis characterized by the deposition of monosodium urate (MSU) crystals in the joints, resulting from a disorder in purine metabolism. It occurs more frequently in men than in women prior to menopause and is rare in young women. Gout can lead to various health complications, with many patients experiencing a significant burden of chronic kidney disease (CKD) and joint deformities. The development of gout is influenced by a complex interplay of genetic, environmental, and lifestyle factors, with elevated serum MSU levels serving as a key risk factor for its onset. However, only 10% of individuals with hyperuricemia go on to develop clinical gout, and several susceptibility loci are associated with the condition. Here, we present a case of a young woman with gouty sacroiliitis and gouty nephropathy linked to susceptibility loci.
Keywords: Gout, Renal abscess, Sacroiliitis, genetic variants, Young woman
Received: 16 Oct 2024; Accepted: 13 Feb 2025.
Copyright: © 2025 Tang, Ling, Jiang, Zhang and Xie. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yubao Jiang, The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China
Jianyong Zhang, The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China
Jingjing Xie, The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China
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