
94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
ORIGINAL RESEARCH article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1507226
This article is part of the Research Topic Imaging in the Diagnosis and Treatment of Eye Diseases View all 15 articles
The final, formatted version of the article will be published soon.
You have multiple emails registered with Frontiers:
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Pterygium is a common eye disease, and accurately assessing its severity and implementing appropriate treatment plans can minimize patient suffering. To address the increasing number of pterygium patients and the relatively limited number of ophthalmologists, it is crucial to develop efficient AI-based diagnostic methods. This paper proposes an automatic pterygium grading system that combines deep learning models with traditional image processing techniques. The system consists of two main components: a semantic segmentation module and a severity assessment module. In the semantic segmentation module, we improved the Transunet network for the specific task, enhancing segmentation performance. In the severity assessment module, we used an improved curve fitting method to calculate the depth of pterygium invasion into critical regions of the eye, serving as a basis for assessing pterygium severity.Our research is based on slit-lamp microscope images of the anterior segment provided by the Ophthalmology Department of the Second Affiliated Hospital of Harbin Medical University. These images were annotated at the pixel level for training the semantic segmentation model. The segmentation model achieved an average Dice coefficient of 94.89 on the test set (with a Dice coefficient of 90.41 for the pterygium class). In the overall evaluation phase, we used additional photos for validation. The system's grading accuracy and weighted F1 score reached 0.9360 and 0.9363, respectively, with the Kappa consistency coefficient between the system and professional physician assessments reaching up to 0.8908, demonstrating the reliability of this method.
Keywords: Pterygium, Semantic segmentation, deep learning, Curve fitting, AI-based diagnostic
Received: 22 Jan 2025; Accepted: 18 Feb 2025.
Copyright: © 2025 Ji, Liu, Ma, He, Zhang and Qu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Lijun Qu, Harbin Medical University, Harbin, 130012, Heilongjiang, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Research integrity at Frontiers
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.