Skip to main content

CASE REPORT article

Front. Med.

Sec. Obstetrics and Gynecology

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1504491

This article is part of the Research Topic Maternal-Fetal Interface Formation and Pregnancy Outcome View all 14 articles

Retained Non-Previa Placenta in The Era of "Placenta Accreta Spectrum": A Report of Two Cases Managed Expectantly and a Proposed Plan for Management

Provisionally accepted
Mohamad K. Ramadan Mohamad K. Ramadan 1Nohad El-Zein Nohad El-Zein 1Murchida Jomaa Murchida Jomaa 1Abeer Zeidan Abeer Zeidan 1Rana El Tal Rana El Tal 1DOMINIQUE A. BADR DOMINIQUE A. BADR 2*
  • 1 Makassed General Hospital, Beirut, Lebanon
  • 2 University Hospital Brugmann, Brussels, Belgium

The final, formatted version of the article will be published soon.

    Retained placenta (RP) is the absence of placental expulsion within 30 minutes of neonatal delivery. It is an obstetric complication affecting 0.5-4.8% of all vaginal deliveries. We report two cases in which the patients were primiparous. Patients were initially kept at the hospital under close observation. The lack of spontaneous detachment and the absence of bleeding prompted us to resort to an expectant approach approved by both patients. A decrease in B-hCG levels was followed by a steady decrease in placental size and the resumption of regular menses. The management of RP should be individualized according to hospital resources, patient fertility desire, sonographic characteristics, the presence of hemorrhage, and hemodynamic stability. RP should prompt the mobilization of resources needed for managing postpartum hemorrhage (PPH), which might ensue without notice.Manual removal of the placenta (MROP) has been recommended for managing RP regardless of hemorrhage or retention etiology. MROP, however, might initiate massive bleeding, infections, prolonged hospitalization, the need for curettage and hysterectomy.Moreover, if MROP is attempted in an unidentified placenta accreta spectrum (PAS), it might initiate life-threatening hemorrhage, necessitating the performance of hemostatic interventions, including emergent hysterectomy. Serious considerations should be given to mitigate the indiscriminate use of MROP in the era of the "PAS epidemic".

    Keywords: Expectant management, Placenta accreta spectrum, placenta adherent, Ultrasonography, Retained placenta

    Received: 30 Sep 2024; Accepted: 04 Apr 2025.

    Copyright: © 2025 Ramadan, El-Zein, Jomaa, Zeidan, El Tal and BADR. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: DOMINIQUE A. BADR, University Hospital Brugmann, Brussels, Belgium

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

    Research integrity at Frontiers

    Man ultramarathon runner in the mountains he trains at sunset

    95% of researchers rate our articles as excellent or good

    Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


    Find out more