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ORIGINAL RESEARCH article
Front. Med.
Sec. Obstetrics and Gynecology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1503836
This article is part of the Research Topic Maternal-Fetal Interface Formation and Pregnancy Outcome View all 11 articles
Analysis of reproductive outcomes after cesarean scar pregnancy surgery: a multicenter retrospective study
Provisionally accepted- 1 Hubei Minzu University, Enshi, China
- 2 Linyi People's Hospital, Linyi, Shandong Province, China
- 3 Henan Provincial People's Hospital, Zhengzhou, Henan Province, China
- 4 Weifang Traditional Chinese Hospital, Weifang, Shandong Province, China
- 5 Weifang People's Hospital, Weifang, Shandong Province, China
【Abstract】Objective: Objective: To analyze the outcome of postoperative re-pregnancies in patients with CSP and to investigate the factors influencing the occurrence of recurrent cesarean section scar pregnancy (RCSP). Methods: A retrospective analysis was performed on the clinical data of 105 patients with CSP who had undergone surgical treatment and were admitted to Minda Hospital affiliated with Hubei University for Nationalities, Henan Provincial People's Hospital, Linyi People's Hospital, and Weifang People's Hospital from January 2015 to May 2021. The reproductive outcomes of these patients were monitored, and the factors influencing the occurrence of RCSP were analyzed. Results: In this study, it was found that the reproductive outcomes of patients with CSP after surgery included ectopic pregnancy, normal intrauterine pregnancy, RCSP, and abortion. The postoperative re-pregnancy rate was 51.72% (105/203), and the postoperative RCSP rate was 13.33% (14/105). The number of cesarean sections (OR = 2.004, 95% CI: 1.412 - 22.579, P < 0.001) was identified as an independent risk factor for the occurrence of RCSP, and the intraoperative removal of the uterine scar (OR = 0.045, 95% CI: 0.005 - 190.400, P = 0.002) was determined as an independent protective factor for the occurrence of RCSP. Conclusion: For patients with residual reproductive requirements after CSP surgery, the removal of uterine scar tissue during the operation can be contemplated. Subsequent postoperative re-pregnancy demands close surveillance and follow-up during gestation, with appropriate termination of pregnancy when warranted. For patients without reproductive needs after surgery, contraception is recommended to prevent the occurrence of RCSP.
Keywords: Cesarean scar pregnancy, postoperative, recurrent cesarean scar pregnancy, Reproductive outcomes, Logis tic regression
Received: 29 Sep 2024; Accepted: 11 Feb 2025.
Copyright: © 2025 Yin, Limei, Nuo, Huagang and Chaoyan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Huang Limei, Linyi People's Hospital, Linyi, Shandong Province, China
Xu Nuo, Henan Provincial People's Hospital, Zhengzhou, 450000, Henan Province, China
Ma Huagang, Weifang Traditional Chinese Hospital, Weifang, Shandong Province, China
Yuan Chaoyan, Hubei Minzu University, Enshi, China
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