ORIGINAL RESEARCH article
Front. Med.
Sec. Intensive Care Medicine and Anesthesiology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1500901
This article is part of the Research TopicInfections in the Intensive Care Unit - Volume IIIView all 10 articles
Prevalence of ventilator-associated pneumonia and associated factors among intubated adult patients admitted in public hospitals in Addis, Ababa, Ethiopia: A facility-based retrospective study design
Provisionally accepted
- St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia
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Background: Ventilator-associated pneumonia (VAP) occurs after 48 hours of intubation or tracheostomy, leading to prolonged mechanical ventilation, increased healthcare costs, antibiotic-resistant bacteria, and increased morbidity and mortality in resource limited setting including Ethiopia. Objectives: This study aimed to determine the prevalence of ventilator-associated pneumonia and associated factors among intubated adult patients admitted in public hospitals in Addis Ababa, Ethiopia, in 2024. Methods: A facility-based retrospective study was conducted on 341 adult patients admitted to the intubated Intensive Care Unit (ICU) from January 1st, 2021 to December 30th, 2023.Variables with a bi-variable analysis with P-values <0.05 considered statistically significant.Result: A total of 335 patient charts were enrolled in the study with a response rate of 98.2%.More than half of the participants 191 (57%) were male. The median age of patients was 40 years . This study determined that the prevalence of Ventilator-Associated Pneumonia (VAP) was 31.3% (95% CI: 26.3 % -36.4 %). This study identified factors increases odds of ventilator-associated pneumonia were age of participants ≥60 years (AOR: 3.
Keywords: 2, 95% CI: 1.51-7.12), being re-intubation (AOR: 4.8, 95% CI: 2.4-9.4), duration of patient on mechanical ventilator (AOR: 3.2, 95% CI: 1.4-7.2), tracheostomy (AOR: 2.5, 95% CI: 1.2-5.2) 2
Received: 25 Sep 2024; Accepted: 28 Mar 2025.
Copyright: © 2025 Demissie, Tegegne and Chekol. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dereje Bayissa Demissie, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia
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