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ORIGINAL RESEARCH article

Front. Med.

Sec. Intensive Care Medicine and Anesthesiology

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1500901

This article is part of the Research Topic Infections in the Intensive Care Unit - Volume III View all 6 articles

Prevalence of ventilator-associated pneumonia and associated factors among intubated adult patients admitted in public hospitals in Addis, Ababa, Ethiopia: A facility-based retrospective study design

Provisionally accepted
  • St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia

The final, formatted version of the article will be published soon.

    Background: Ventilator-associated pneumonia (VAP) occurs after 48 hours of intubation or tracheostomy, leading to prolonged mechanical ventilation, increased healthcare costs, antibiotic-resistant bacteria, and increased morbidity and mortality in resource limited setting including Ethiopia. Objectives: This study aimed to determine the prevalence of ventilator-associated pneumonia and associated factors among intubated adult patients admitted in public hospitals in Addis Ababa, Ethiopia, in 2024. Methods: A facility-based retrospective study was conducted on 341 adult patients admitted to the intubated Intensive Care Unit (ICU) from January 1st, 2021 to December 30th, 2023.Variables with a bi-variable analysis with P-values <0.05 considered statistically significant.Result: A total of 335 patient charts were enrolled in the study with a response rate of 98.2%.More than half of the participants 191 (57%) were male. The median age of patients was 40 years . This study determined that the prevalence of Ventilator-Associated Pneumonia (VAP) was 31.3% (95% CI: 26.3 % -36.4 %). This study identified factors increases odds of ventilator-associated pneumonia were age of participants ≥60 years (AOR: 3.

    Keywords: 2, 95% CI: 1.51-7.12), being re-intubation (AOR: 4.8, 95% CI: 2.4-9.4), duration of patient on mechanical ventilator (AOR: 3.2, 95% CI: 1.4-7.2), tracheostomy (AOR: 2.5, 95% CI: 1.2-5.2) 2

    Received: 25 Sep 2024; Accepted: 28 Mar 2025.

    Copyright: © 2025 Demissie, Tegegne and Chekol. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Dereje Bayissa Demissie, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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