Skip to main content

ORIGINAL RESEARCH article

Front. Med.
Sec. Intensive Care Medicine and Anesthesiology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1492210

Effect of rapid rehabilitation surgery (ERAS) on postoperative rehabilitation, complications and long-term prognosis in radical laryngectomy: A PSM matching study

Provisionally accepted
Teng He Teng He 1*Yibo Huang Yibo Huang 1Meifang Wang Meifang Wang 1Jianfeng Pu Jianfeng Pu 1Yunpeng Zang Yunpeng Zang 2
  • 1 Affiliated changshu hospital of Nantong University, Changshu, China
  • 2 The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    Objective: To evaluate the effects of Enhanced Recovery After Surgery (ERAS) on postoperative rehabilitation, complications, and long-term prognosis in patients undergoing radical laryngectomy using a single-center propensity score matching (PSM) study.Methods: A retrospective cohort study included patients newly diagnosed with laryngeal cancer between January 1, 2019, and January 1, 2021, scheduled for partial laryngectomy. The control group (CG) comprised patients treated with standard interventions in 2019, while the research group (RG) included patients undergoing ERAS in 2020. After exclusions, 233 individuals remained: 94 in the RG and 204 in the CG. Following PSM in a 2:1 ratio, there were 180 in the CG and 90 in the RG. Relevant indices were analyzed.Results: No significant differences were found in baseline characteristics (P > 0.05). The RG showed significantly lower hospital stay, nasogastric tube and tracheal cannula duration, early enteral nutrition, hospitalization expenses, and readmission rates compared to the CG (P < 0.05). The RG had higher albumin and prealbumin levels on postoperative days 3 and 7 (P < 0.05) but not on day 1 (P > 0.05). No significant differences were found in 1-year or 2-year overall survival rates, nor in recurrence-free survival rates between the groups (P > 0.05), though the RG showed marginally better survival.Conclusion: ERAS treatment for postoperative laryngeal cancer patients reduces hospitalization duration, nasogastric tube and tracheal cannula use, costs, readmission rates, and complications, while accelerating recovery and facilitating early discharge. ERAS enhances patient comfort and clinical outcomes, supporting broader clinical adoption.

    Keywords: Rapid rehabilitation surgery, radical laryngectomy, postoperative rehabilitation, Long-term prognosis, PSM matching

    Received: 06 Sep 2024; Accepted: 29 Jan 2025.

    Copyright: © 2025 He, Huang, Wang, Pu and Zang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Teng He, Affiliated changshu hospital of Nantong University, Changshu, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.