Evaluation of Deep Vein Thrombosis Prophylaxis Use in a Northwest Ethiopian Medical Ward: An Observational Follow-up Study

Samuel Dagnew ^* Tilaye Arega Moges Fisseha Nigussie Abraham Assefa Sisay Sitotaw Adane Tsegaw Geremew Getu Tesfaw Addis

• Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia

In hospitalization, a significant number of patients at risk for thromboembolism do not receive prophylaxis even despite established standards and viable procedures for preventing deep vein thrombosis. This study aimed to assess the appropriateness of vein thrombosis prophylaxis use among patients admitted to the medical ward of the Debre Taborabor comprehensive specialized hospital in Northwest Ethiopia.An observational follow-up study was conducted in the medical wards of the Debre Tabor Comprehensive Specialized Hospital in Northwest Ethiopia. It was determined whether thromboprophylaxis was appropriate using the Padua Risk Assessment tool. To identify factors for the occurrence of inappropriate thromboprophylaxis use, a binary logistic regression model was employed. When P < 0.05 with a 95% confidence interval, statistics were considered significant.Of the 365 patients included, 21.37% used inappropriate thrombophylaxis, and 78.63% were found to be managed by the provision of interventions. Patients admitted to the ICU [AOR = 4.276,; p = 0.000], patients who stayed for more than six days [AOR =6.192, 95% CI: 2.085 -14.391; p = 0.000], and general practitioners [AOR = 1.816, 95% CI: 1.007 -3.207; p = 0.048] were more likely to use inappropriately the inappropriate.The appropriateness of DVT prophylaxis use was suboptimal, especially for patients treated by general practitioners, those hospitalized in the intensive care unit, and those confined for longer than a few days in the ward. Using an integrated risk stratification checklist is a good way to increase the usage of DVT prophylaxis more rationally.