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ORIGINAL RESEARCH article

Front. Med.
Sec. Nephrology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1434543
This article is part of the Research Topic Advancements and Challenges in Resuscitation and Cardiac Emergency Medicine View all 5 articles

Preexisting hemodialysis and survival outcome in out-of-hospital cardiac arrest patients: Ulsan, South Korea

Provisionally accepted
Song Yi Park Song Yi Park 1Sun Hyu Kim Sun Hyu Kim 2*Byungho Choi Byungho Choi 2
  • 1 Department of Emergency Medicine, Dong-A University College of Medicine, Dong-A University Hospital, Busan, Republic of Korea
  • 2 Department of Emergency Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Republic of Korea

The final, formatted version of the article will be published soon.

    Background: Although the incidence of sudden cardiac death is higher in hemodialysis (HD) patients, whether out-of-hospital cardiac arrest (OHCA) survival outcomes are poorer in this group remains unclear. This study aimed to assess the impact of HD on survival outcomes among adult nontraumatic OHCA patients and to compare these outcomes between HD and non-HD groups.Methods: This observational cohort study retrospectively analyzed data from adult nontraumatic OHCA patients in Ulsan, South Korea, from January 2017 through December 2022. Multivariable logistic regression analysis was applied to evaluate whether HD was a risk factor for survival in OHCA patients. Survival was compared between the two groups in unadjusted, balanced groups by propensity score matching (PSM) and inverse probability of the treatment weighting (IPWT).The study included 2,489 patients (64 HD group and 2,425 non-HD group). Undergoing HD was not significantly associated with any return of spontaneous circulation (ROSC) (adjusted odds ratio [95% confidence interval], p-value, 1.648 [0.934-2.907], p = 0.085), survival to discharge (1.544 [0.734-3.250], p = 0.252), or neurological outcomes (0.394 [0.017-9.346], 0.564). There were also no significant differences observed in any ROSC (1.648 [0.934-2.907], p = 0.085), survival to discharge (1.544 [0.734-3.250], p = 0.252), or favorable neurological outcome (0.394 [0.017-9.346], p = 0.564) between the two unadjusted groups. The insignificant survival differences were persistently observed in the PSM group and IPWT group.Although HD may pose a risk factor for cardiac arrest, our study did not find a significant association with survival outcomes in OHCA patients. Additionally, no notable survival difference was observed between HD and non-HD groups. Therefore, resuscitation efforts in HD patients should not be underestimated.

    Keywords: cardiopulmonary resuscitation1, out-of-hospital cardiac arrest2, renal dialysis3, acute kidney injury4, treatment outcome5

    Received: 18 May 2024; Accepted: 03 Jan 2025.

    Copyright: © 2025 Park, Kim and Choi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Sun Hyu Kim, Department of Emergency Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Republic of Korea

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