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MINI REVIEW article

Front. Med.
Sec. Dermatology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1538373
This article is part of the Research Topic From dyslipidemia to acne vulgaris: A call for new directions View all articles

Current perspectives for metabolomics and lipidomics in dyslipidemia of acne vulgaris: A mini review

Provisionally accepted
Liang Wu Liang Wu 1Shengcai Zhu Shengcai Zhu 1Yang He Yang He 1Yunxia Zhu Yunxia Zhu 1XiaoLiang OuYang XiaoLiang OuYang 1Deng Zhang Deng Zhang 2Chunming Li Chunming Li 1*
  • 1 Nanchang University, Nanchang, China
  • 2 Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

    Acne vulgaris (AV) is a common inflammatory disorder involving the pilosebaceous unit. Many studies have reported that people with AV have higher levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-c) compared to healthy controls. Hence, they concluded that an unhealthy lipid profile is an independent risk factor for AV. Recent research in metabolomics and lipidomics has been propelled by rapid advancements in technologies including computational methods and mass spectrometry. Using metabolomics and lipidomics approach, a broad range of structurally diverse lipid species were detected and important lipid biomarkers were identified that are vital to the pathogenesis of AV. In this review, we will describe the recent progress in dyslipidemia of AV using metabolomics and lipidomics advances. We will begin with a literature overview of dyslipidemia of AV, followed by a short introduction of metabolomics and lipidomics. Finally, we will focus on applying metabolomics and lipidomics in dyslipidemia of AV.

    Keywords: Acne Vulgaris, Dyslipidemia, Metabolomics, lipidomics, Sphingomyelins, Phosphatidylcholines

    Received: 02 Dec 2024; Accepted: 27 Dec 2024.

    Copyright: © 2024 Wu, Zhu, He, Zhu, OuYang, Zhang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Chunming Li, Nanchang University, Nanchang, China

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