Qunying Yang
XiangHong Jin
*The final, formatted version of the article will be published soon.
CASE REPORT article
Front. Med.
Sec. Gastroenterology
Volume 11 - 2024 |
doi: 10.3389/fmed.2024.1519819
This article is part of the Research Topic Chronic Atrophic Gastritis: Pathogenesis, Diagnostic Challenges, and Gastric Cancer Risk View all articles
Autoimmune gastritis diagnosed due to recurrent gastric neuroendocrine tumor: A case report
Provisionally accepted- Dongyang People’s Hospital, Dongyang, China
As digestive endoscopy becomes more prevalent, an increasing number of autoimmune gastritis (AIG) cases have been diagnosed, which has contributed to a growing body of research on AIG. We report the case of a patient with AIG who was diagnosed due to receiving endoscopic surgery after discovering a gastric neuroendocrine tumor (GNET) during gastroscopy twice within 3 years. The patient was admitted to our hospital for endoscopic submucosal dissection (ESD) due to GNET recurrence discovered during gastroscopy. The patient had previously undergone ESD due to a GNET discovered during gastroscopy three years ago. Recent repeat gastroscopy revealed severe mucosal atrophy in the gastric body and fundus, an ulcer in the gastric antral, and two mucosal bulges in the gastric body. Pathology indicated Grade 2 (G2)-GNET, and ESD was performed again. The patient also had iron deficiency anemia and thyroid dysfunction, elevated gastrin, and decreased pepsinogen I (PG I) and PG I/II. Hence, AIG was diagnosed.Recurrent GNET cases, especially those with concurrent anemia and abnormal thyroid function, may experience AIG. In addition to symptomatic treatment, the clinician must evaluate the patient's overall condition.
Keywords: Autoimmune gastritis, atrophic gastritis, gastric neuroendocrine tumors, Endoscopic Submucosal Dissection, gastrin
Received: 30 Oct 2024; Accepted: 06 Dec 2024.
Copyright: © 2024 Yang, Jin, Lv and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
XiangHong Jin, Dongyang People’s Hospital, Dongyang, China
XiangYing Lv, Dongyang People’s Hospital, Dongyang, China
JianWen Hu, Dongyang People’s Hospital, Dongyang, China
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