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CASE REPORT article

Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1514241

A case of severe lower limb necrotizing fasciitis caused by an insulin injection has been reported.

Provisionally accepted
Yang Ma Yang Ma Jinshuo Tang Jinshuo Tang Fei Wang Fei Wang Enbo Liu Enbo Liu Jianlin Zuo Jianlin Zuo *
  • China-Japan Union Hospital, Jilin University, Changchun, China

The final, formatted version of the article will be published soon.

    Necrotizing fasciitis (NF) is a rare but life-threatening soft tissue infection, often accompanied by severe systemic toxicity. Early detection and prompt treatment are critical for survival. We report a case of NF in a 53-year-old diabetic woman following a subcutaneous insulin injection in the thigh. The patient presented with severe local pain as the initial symptom, and Escherichia coli was the sole isolated pathogen, which is seldom reported in the current literature. We combined with existing literature and clinical manifestations observed in NF patients at our hospital, offer valuable guidance for clinicians in recognizing and responding to NF.

    Keywords: Necrotizing Fasciitis (NF), Escherichia coli, finger separation test;, Vacuum sealing drainage (VSD), diabetes, Insulin injection

    Received: 20 Oct 2024; Accepted: 16 Dec 2024.

    Copyright: © 2024 Ma, Tang, Wang, Liu and Zuo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jianlin Zuo, China-Japan Union Hospital, Jilin University, Changchun, China

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