Skip to main content

ORIGINAL RESEARCH article

Front. Med.
Sec. Geriatric Medicine
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1508868

Association between albumin changes and prognosis in older patients with acute myocardial infarction

Provisionally accepted
Zhi-cheng Yang Zhi-cheng Yang 1Lei Zhang Lei Zhang 2Ying-bin Xi Ying-bin Xi 3Gui-Hua Jiang Gui-Hua Jiang 2He Lin He Lin 4Hui Pan Hui Pan 4Zhi-hao Wang Zhi-hao Wang 4*
  • 1 School of Nursing and Rehabilitation, Shandong University, Jinan, Shandong Province, China
  • 2 Department of Cardiology, Qilu Hospital of Shandong University, Jinan, Shandong Province, China
  • 3 The Affiliated Weihai Second Municipal Hospital of Qingdao University, Weihai, Shandong, Weihai, China
  • 4 Qilu Hospital, Shandong University, Jinan, China

The final, formatted version of the article will be published soon.

    Background and aims: Acute myocardial infarction (AMI) is the leading cause of death in the world. Therefore, early identification of the prognosis of older patients with AMI are particularly urgent, and better to improve treatment. This study aimed to explore the association between albumin changes and prognosis in older patients with AMI.Outcomes included all-cause death during hospitalization, cardiac death, gastrointestinal hemorrhage, nonfatal myocardial infarction, acute heart failure, and severe arrhythmia. Multivariable-adjusted Cox regression analysis and curve fitting were used to assess the relationship between albumin changes and prognosis in patients with AMI.Results: Our study included 288 older patients with AMI. A S-shaped association between the albumin changes and mortality of patients with AMI was found. For all-cause death, we found two inflection points were -3.27 and 0.92g/L. On the left side of -3.27 g/L, the OR was 0.41 (OR: 0.41,

    Keywords: albumin changes, acute myocardial infarction, older people, prognosis, S-shaped

    Received: 10 Oct 2024; Accepted: 26 Dec 2024.

    Copyright: © 2024 Yang, Zhang, Xi, Jiang, Lin, Pan and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhi-hao Wang, Qilu Hospital, Shandong University, Jinan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.