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ORIGINAL RESEARCH article

Front. Med.
Sec. Pathology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1507100
This article is part of the Research Topic Glycolipid Metabolism Disorders in Cerebrovascular and Cardiovascular Diseases: Advanced Insights Into Pathology, Pathophysiology and Treatment View all 3 articles

Cardiometabolic index is associated with heart failure: a cross-sectional study based on NHANES Runing Title: CMI and HF

Provisionally accepted
Xiao-Ming Zhu Xiao-Ming Zhu Yan Xu Yan Xu Jie Zhang Jie Zhang *
  • Wuxi Xishan People′s Hospital, Jangsu, China

The final, formatted version of the article will be published soon.

    Heart failure is a complex syndrome characterized by impaired cardiac function, resulting in insufficient cardiac output to meet metabolic demands. Despite improvements in treatment, the prevalence of heart failure continues to rise, driven by aging populations and increased risk factors. The Cardiometabolic Index (CMI), a novel measure combining abdominal obesity and lipid levels, has emerged as a potential predictor of cardiac metabolic risk. This study utilized data from the NHANES database, analyzing 22,586 participants to investigate the association between CMI and heart failure. Results revealed a significant positive correlwation: as CMI increased, so did the risk of heart failure, with odds ratios of 2.77 and 1.87 for the highest quartile after adjusting for confounders. Subgroup analyses indicated heightened risks among older adults and those with hypertension or diabetes. ROC curve analysis demonstrated that CMI offers good diagnostic efficacy for heart failure, surpassing traditional measures like BMI. Our findings suggest that CMI is a valuable tool for assessing heart failure risk, highlighting the importance of addressing cardiac metabolic health in prevention and treatment strategies. Further research is needed to explore causal relationships and refine predictive models incorporating CMI.

    Keywords: Heart Failure, Cardiometabolic index, NHANES, Prevention strategies, Lipids

    Received: 07 Oct 2024; Accepted: 25 Nov 2024.

    Copyright: © 2024 Zhu, Xu and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jie Zhang, Wuxi Xishan People′s Hospital, Jangsu, China

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