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CASE REPORT article

Front. Med.
Sec. Obstetrics and Gynecology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1504772
This article is part of the Research Topic Maternal-Fetal Interface Formation and Pregnancy Outcome View all 11 articles

Managing two cases of twin anemia-polycythemia sequence in monochorionic twin pregnancies

Provisionally accepted
Yongke Zhang Yongke Zhang 1*Yiheng Liang Yiheng Liang 1*Ran Chen Ran Chen 2*Dirong Zhang Dirong Zhang 2Jing Wu Jing Wu 3*
  • 1 Department of Obstetrics and Gynecology, Shenzhen Hospital, Peking University, Shenzhen, China
  • 2 Department of Ultrasound Imaging, Shenzhen Hospital, Peking University, Shenzhen, China
  • 3 Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China, Guangzhou, China

The final, formatted version of the article will be published soon.

    Background: Twin anemia-polycythemia sequence (TAPS) is a rare monochorionic complication. In this study, we discuss the management of two cases of TAPS with different conditions.Case Presentation: Patient 1 was a 34-year-old multigravida in whom the fetal middle cerebral artery peak systolic velocities (MCA-PSVs) were 0.86 multiples of the median (MoM) and 2.0 MoM at 33 weeks of gestation. After cesarean section, stage 3 TAPS was confirmed according to the ultrasound findings and hemoglobin results of the newborns and placenta examination after birth. Patient 2 was a nulligravida who was diagnosed with stage 2 TAPS at 18 weeks of gestation. The patient underwent fetoscopic laser surgery. Ultrasonography monitoring of the MCA-PSVs was performed on a schedule after surgery, with a good status but selective intrauterine growth restriction of one cotwin. The newborns reached their normal development milestones after spontaneous preterm birth.Optimal management should be carefully selected for patients with different TAPS conditions.

    Keywords: monochorionic twin pregnancy, Twin anemia-polycythemia sequence (TAPS), Middle cerebral artery peak systolic velocity (MCA-PSV), fetoscopic laser therapy, Ultrasound monitoring

    Received: 01 Oct 2024; Accepted: 11 Nov 2024.

    Copyright: © 2024 Zhang, Liang, Chen, Zhang and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yongke Zhang, Department of Obstetrics and Gynecology, Shenzhen Hospital, Peking University, Shenzhen, China
    Yiheng Liang, Department of Obstetrics and Gynecology, Shenzhen Hospital, Peking University, Shenzhen, China
    Ran Chen, Department of Ultrasound Imaging, Shenzhen Hospital, Peking University, Shenzhen, 518036, China
    Jing Wu, Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China, Guangzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.