Tong Jiang ¹ Zhi-Yu Dong ² Ying Shi ¹ Yangqing Zhou ¹ Hong-Bin Zhang ² Yi Gong ^1*

• ¹ Beilun District People's Hospital of Ningbo, Ningbo, Zhejiang Province, China
• ² Taizhou Traditional Chinese Medicine Hospital, Taizhou, China

Objectives: This systematic review and meta-analysis evaluated the efficacy and safety of acupuncture individually or combined with PFMT in improving symptoms and women's health-related quality of life of SUI. Design: A systematic review and meta‐analysis were conducted. Patients: Women with stress urinary incontinence were treated with electroacupuncture (EA) individually or acupuncture combined with PFMT. Results: In the analysis comparing urinary leakage 1 hour and the ICIQ-SF score, electroacupuncture (EA) intervention was significantly associated with improvements in both urinary leakage (MD=3.32, 95% CI 2.47 to 3.18, I²=40%) and ICIQ-SF (MD=2.67, 95% CI 1.69 to 3.65, I²=50%). The results were robust for the sensitivity analyses. EA was not associated with an increased incidence of adverse events compared to placebo EA (RR=1.08, 95% CI 0.50 to 2.35, I²=0%). When comparing the group receiving pelvic floor muscle training (PFMT) combined with acupuncture to the PFMT only group, the combination therapy was found to enhance urinary leakage 1 hour (MD=1.91, 95% CI 0.96 to 2.86, I²=80%) and improve ICIQ-SF (MD=2.63, 95% CI 1.60 to 3.65, I²=75%) in patients with SUI, despite significant heterogeneity observed. Subgroup analyses based on urinary leakage 1 hour revealed that subjects with mild stress urinary incontinence showed improvements (MD=1.46, 95% CI 0.82 to 2.10, I²=58%), as did those with moderate stress urinary incontinence (MD=4.9, 95% CI 1.72 to 8.08, I²=77%). There were significant differences between these subgroups (I²=77%, p=0.04). In the subgroup analysis of intervention types, manual acupuncture showed no significant effect when combined (MD=1.11, 95% CI -0.61 to 2.83, I²=86%) Conclusion: The findings from this meta-analysis indicate that EA is more effective at improving the clinical symptoms and quality of life in patients with SUI compared to placebo EA, and it does not increase the risk of adverse events. Moreover, the therapeutic effect of SUI treatment with acupuncture combined with pelvic floor muscle training (PFMT) elicits a more positive response than PFMT alone. This suggests that acupuncture, either as a standalone therapy or as an adjunct to PFMT, can offer beneficial outcomes for individuals with stress urinary incontinence, expanding the range of clinical treatment options available