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CASE REPORT article

Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1495324

VV-ECMO adjuvant therapy for Leptospira complicated with H1N1 infection: a case report

Provisionally accepted
Yuchou Zhang Yuchou Zhang HanChun Wen HanChun Wen *
  • First Affiliated Hospital, Guangxi Medical University, Nanning, China

The final, formatted version of the article will be published soon.

    Leptospirasis is an acute infectious disease that occurs rapidly, progresses rapidly, and has a high mortality rate, with an estimated 1.2 million new cases and nearly 59000 deaths each year. Due to its diverse clinical manifestations, diagnosis is often delayed. Therefore, it is necessary to pay attention to its clinical manifestations, diagnostic methods, and treatment methods.A 51 year old male from the Han ethnic group experienced fever, chills, headache, and overall fatigue after being exposed to rain, followed by yellowing of the skin and worsening of breathing difficulties. mNGS indicates infection with leptospirosis and influenza A. After 5 days of treatment with VV-ECMO, Penicillium, and Oseltamivir, the condition improved.Improved with VV-ECMO support and anti-infective treatment with penicillin and oseltamivir. VV-ECMO provides a therapeutic time window for rescue, and mNGS lays a foundation for early detection of etiology.

    Keywords: Leptospirosis, H1N1, VV-ECMO, ICU, penicillin, MNGs

    Received: 16 Sep 2024; Accepted: 11 Dec 2024.

    Copyright: © 2024 Zhang and Wen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: HanChun Wen, First Affiliated Hospital, Guangxi Medical University, Nanning, China

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