Skip to main content

ORIGINAL RESEARCH article

Front. Med.
Sec. Pathology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1494768

The Diagnosis and Treatment of 56 Cases of Breast Hamartoma: A Single-Center Analysis and a Review of the Literature

Provisionally accepted
Hao Su Hao Su Caiyun Bai Caiyun Bai *Zhimin Fan Zhimin Fan Di Wu Di Wu *Fengjiang Qu Fengjiang Qu *
  • First Affiliated Hospital of Jilin University, Changchun, China

The final, formatted version of the article will be published soon.

    To analyze and summarize the clinical and pathological features of breast hamartoma to enhance clinicians' awareness of this rare and benign lesion of the breast.We retrospectively described the clinical data, imaging results, and pathological findings of 56 patients with breast hamartoma who underwent surgical treatment at the First Hospital of Jilin University between January 2005 and December 2020, and summarized the features. Additionally, a literature review was conducted using the PubMed database for clinical reports on breast hamartoma and analyzed them.Results: This study included 56 female patients. Preoperative ultrasound revealed round or elliptical heterogeneous echoes with clear boundaries: hypoechoic in 35 cases (63%), iso-echoic in 8 cases (14%), hyperechoic in 1 case (2%), mixed echo in 9 cases (16%), slightly strong echo in 1 case (2%), and uneven echo of fat in 2 cases (4%).Mammography was performed in 33 cases, revealing clear and dense shadows in 20 cases (61%) and dense shadows on the outer edges in 16 cases (48%). The excised masses were solid, with light yellow and gray cut surfaces. Pathological analysis identified ducts and fibrous tissue, with intra-tumoral fat content ranging from 10% to 90%.Breast hamartoma is prevalent among perimenopausal women and is characterized by ultrasound and radiography; surgical intervention remains the primary treatment with a good prognosis.

    Keywords: breast hamartoma, Misdiagnosis, Treatment, ultrasound imaging, Pathological analysis

    Received: 10 Oct 2024; Accepted: 26 Dec 2024.

    Copyright: © 2024 Su, Bai, Fan, Wu and Qu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Caiyun Bai, First Affiliated Hospital of Jilin University, Changchun, China
    Di Wu, First Affiliated Hospital of Jilin University, Changchun, China
    Fengjiang Qu, First Affiliated Hospital of Jilin University, Changchun, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.