Skip to main content

ORIGINAL RESEARCH article

Front. Med.
Sec. Gastroenterology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1489117
This article is part of the Research Topic Gastrointestinal Tract Infections: A Global Perspective View all 16 articles

Potential application of ChatGPT's in Helicobacter pylori disease relevant queries

Provisionally accepted
Zejun Gao Zejun Gao Jinlin Ge Jinlin Ge Ruoshi Xu Ruoshi Xu Xiaoyan Chen Xiaoyan Chen *Zhenzhai Cai Zhenzhai Cai *
  • Department of Gastroenterology, Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China

The final, formatted version of the article will be published soon.

    Background: Advances in artificial intelligence are gradually transforming various fields, but its applicability among ordinary people is unknown. This study aims to explore the ability of a large language model to address Helicobacter pylori related questions. Methods: We created several prompts on the basis of guidelines and the clinical concerns of patients. The capacity of ChatGPT on Helicobacter pylori queries was evaluated by experts. Ordinary people assessed the applicability. Results: The responses to each prompt in ChatGPT-4 were good in terms of response length and repeatability. There was good agreement in each dimension (Fleiss’ kappa ranged from 0.302-0.690, p<0.05). The accuracy, completeness, usefulness, comprehension and satisfaction scores of the experts were generally high. Rated usefulness and comprehension among ordinary people were significantly lower than expert, while medical students gave a relatively positive evaluation. Conclusions: ChatGPT-4 performs well in resolving Helicobacter pylori related questions. Large language models may become an excellent tool for medical students in the future, but still requires further research and validation.

    Keywords: Helicobacter pylori, intrafamilial transmission, ChatGPT, Large Language Model, Artificial intelligence.

    Received: 31 Aug 2024; Accepted: 27 Sep 2024.

    Copyright: © 2024 Gao, Ge, Xu, Chen and Cai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Xiaoyan Chen, Department of Gastroenterology, Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
    Zhenzhai Cai, Department of Gastroenterology, Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.