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SYSTEMATIC REVIEW article

Front. Med.
Sec. Pulmonary Medicine
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1488796

Bibliometric Analysis of Pyroptosis in Pathogenesis and Treatment of Acute Lung Injury

Provisionally accepted
Chun Wang Chun Wang Na Liu Na Liu *
  • Second Affiliated Hospital of Dalian Medical University, Dalian, China

The final, formatted version of the article will be published soon.

    Objective: This study aims to conduct a bibliometric analysis to assess the present state, thematic focus, and emerging developments in the research literature on the involvement of pyroptosis in the pathogenesis and treatment of acute lung injury (PFALI), as well as other pertinent research areas. Methods: This bibliometric study examined PFALI research published from January 1, 2004 to May 24, 2024, utilizing the Web of Science database. The analysis was conducted using CiteSpace, VOSviewer, R, and GraphPad Prism 8.0, and encompassed metadata on the countries, institutions, authors, journals, and keywords represented in the literature. Results: This study analyzed 1,495 publications, comprising 1,194 articles and 301 reviews, to assess the publication output on PFALI. China exhibited the highest output with 964 (64.48%) articles. Central South University was the most prolific institution, contributing 54 (3.61%) publications. Zhou, Yong had the greatest individual publication record, with 15 (3.59%) articles. The journal International Immunopharmacology published the most PFALI-related articles at 76 (5.09%). The identified research frontiers for upcoming years include "iron", "sirt1", "repair", and "alveolar macrophage pyroptosis". Conclusion: This bibliometric analysis comprehensively examined research trends and advancements related to PFALI, including the contributions of key authors, institutions, and countries.

    Keywords: Acute Lung Injury, pyroptosis, Inflammasome, Nrf2 signaling pathway, targeted therapy

    Received: 30 Aug 2024; Accepted: 31 Dec 2024.

    Copyright: © 2024 Wang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Na Liu, Second Affiliated Hospital of Dalian Medical University, Dalian, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.