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CASE REPORT article

Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1481388
This article is part of the Research Topic Diabetic Wound: Multifaceted Mechanisms and Future of Diabetic Wound Healing, Volume II View all 6 articles

A Novel Approach of Using Transtibial Transport (TTT) to Manage Thromboembolic Events Following Surgical Management of Necrotising Soft Tissue Infection: A Case Report

Provisionally accepted
  • 1 Dr Foot Podiatry, Singapore, Singapore
  • 2 Shenzhen Hospital, Peking University, Shenzhen, Beijing Municipality, China

The final, formatted version of the article will be published soon.

    Necrotising soft tissue infections (NSTIs) are one of the most challenging and severe forms of infections. The prognosis requires accurate and aggressive diagnosis and management. In this case, we present an unexplained case of concurrence of TE events following BKA for the surgical management of NSTI. As with the standard management, the first step involves aggressive surgical debridement of nonviable tissue which eventually lead to below-knee amputation for effective source control. Lower limb endovascular angioplasty was attempted but unsuccessful. The PAD was managed with antithrombotic therapy. In spite of this, the patient developed thromboembolic events one week following BKA. In response, the antiplatelet therapy with low-molecular weight heparin was enhanced.Transtibial transport was performed after patient found to have stenosis in distal tibial arteries, which the patient refused any further vascular intervention. Nonetheless, with meticulous planning and concerted team efforts, we successfully reversed TE events and salvaged the contralateral limb without the need for amputation. With intensive rehabilitation, the patient was able to return to their pre-morbid functional quality of life.

    Keywords: diabetic limb salvage, Pulmonary Embolism, Acute limb ischemia, Gangrene, transtibial transport, Bone transport

    Received: 24 Sep 2024; Accepted: 20 Dec 2024.

    Copyright: © 2024 Boey, Lee and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: ZheGang Zhou, Shenzhen Hospital, Peking University, Shenzhen, 518036, Beijing Municipality, China

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