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ORIGINAL RESEARCH article

Front. Med.
Sec. Rheumatology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1470996
This article is part of the Research Topic Rehabilitation and Alternative Medicine in the Healthcare for Chronic Rheumatic Pain Disorders View all 11 articles

EFFECTIVENESS REHABILITATIVE THERAPY AND PRIDINOL MESYLATE IN LOW BACK PAIN

Provisionally accepted
Dalila Scaturro Dalila Scaturro 1*Lorenza Lauricella Lorenza Lauricella 2Noemi Calabrese² Noemi Calabrese² 3Domenico Migliorino Domenico Migliorino 3Michele Vecchio Michele Vecchio 4Giulia Letizia Mauro³ Giulia Letizia Mauro³ 1
  • 1 Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy
  • 2 University Hospital of Palermo, Palermo, Italy
  • 3 University of Catania, Catania, Italy
  • 4 Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy, Catania, Italy

The final, formatted version of the article will be published soon.

    Spondylarthritis is a degenerative disease involving the intervertebral disc, vertebral bodies, and adjacent soft tissues. Treatment aims to slow disease progression and manage symptoms through an interdisciplinary approach. It can be conservative and rarely chirurgic.This study aimed to evaluate the effectiveness of a rehabilitation combined with Pridinol Mesylate in the treatment of Spondylarthritis in elderly patients in terms of pain resolution, improving disability, and quality of life.We conducted a retrospective study on patients with Spondylarthritis.The patients recruited (n=86) were divided into three groups: the Combined Group (CG:28), who received a rehabilitation combined with Pridinol Mesylate (16 women and 12 men, age 66.4± 3.99); the Rehabilitation Group (RG, n=26), who received only rehabilitation (14 women and 12 men, age 66.2± 3.84); and the Drug Group (DG: 32), who received only the administration of the Pridinol(18 women and 14 men, age of 66.3± 3.9).The results show, at T1 (20 days after treatment) in the CG, statistically significant improvements for the NRS and QBPDS. In the RG, statistically significant improvements were observed only for the QBPDS scale. In the DG group, only pain improvement. At T2 (90 days after treatment), the CG showed improvements in NRS, QBPDS, and (SF-36). The RG and DG showed improvements for NRS and for QBPDS. By Bonferroni method, obtained statistically significant values for CG versus RG and for CG versus DG. No statistical significance was found between RG versus DG.Targeted rehabilitation treatment, combined with Pridinol Mesylate, reduced pain and improved disability in lumbar Spondylarthritis both in the short and medium term, with improved quality of life in elderly patients.

    Keywords: Pridinol, Low Back Pain, Postural Balance, Exercise, Rehabilitation

    Received: 26 Jul 2024; Accepted: 04 Dec 2024.

    Copyright: © 2024 Scaturro, Lauricella, Calabrese², Migliorino, Vecchio and Letizia Mauro³. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Dalila Scaturro, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy

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