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CASE REPORT article

Front. Med.
Sec. Hepatobiliary Diseases
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1470419
This article is part of the Research Topic Liver Cancer Awareness Month 2024: Current Progress and Future Prospects on Advances in Primary Liver Cancer Investigation and Treatment View all 4 articles

Primary Hepatic Carcinosarcoma: A Case Report with Insights from Retrospective Analysis of Clinical Characteristics and Prognostic Factors

Provisionally accepted
Zonglei Zhao Zonglei Zhao *Tao Wang Tao Wang Zhexuan Sun Zhexuan Sun Xuefeng Cao Xuefeng Cao *Xingyuan Zhang Xingyuan Zhang
  • Binzhou Medical University Hospital, Binzhou, China

The final, formatted version of the article will be published soon.

    Primary hepatic carcinosarcoma (HCS) is an extremely rare malignant tumor with carcinomatous and sarcomatous elements. Few reported cases of HCS exist, especially with sufficient records to describe imaging and pathological features, making the diagnosis, treatment, and prognosis of HCS a significant challenge for physicians. Here, we report a case of HCS with spontaneous rupture as the initial symptom in a 77-year-old elderly male who was admitted with right upper abdominal pain for eight days. The computed tomography enhancement scan revealed one intrahepatic enhancement with mixed density and a massive, enhanced shadow located mainly outside the liver. We performed a hepatectomy of segment 4 through a laparotomy. The postoperative pathology results demonstrated HCS. The patient recovered smoothly and was discharged after surgery. However, the patient experienced a recurrence and died five months after surgery. This case underscores the importance of identifying high-risk populations and personalized treatment strategies in HCS cases.

    Keywords: primary hepatic carcinosarcoma, Liver tumor, Risk factors, prognosis, case report, nomogram

    Received: 25 Jul 2024; Accepted: 18 Dec 2024.

    Copyright: © 2024 Zhao, Wang, Sun, Cao and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Zonglei Zhao, Binzhou Medical University Hospital, Binzhou, China
    Xuefeng Cao, Binzhou Medical University Hospital, Binzhou, China

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