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REVIEW article

Front. Med.
Sec. Rheumatology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1469964
This article is part of the Research Topic New insights into the role of imaging in large vessel vasculitis View all 9 articles

An overview of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in giant cell arteritis (GCA)

Provisionally accepted
Thomas THIBAULT Thomas THIBAULT 1,2Jean-Louis ALBERINI Jean-Louis ALBERINI 3,4Anne-Claire BILLET Anne-Claire BILLET 5Hélène GREIGERT Hélène GREIGERT 6,7,8Andre RAMON Andre RAMON 8,9Hervé Devilliers Hervé Devilliers 1,2Alexandre COCHET Alexandre COCHET 3,4Bernard Bonnotte Bernard Bonnotte 1,8Maxime SAMSON Maxime SAMSON 1,8*
  • 1 Department of Internal Medicine and Systemic Disease, Dijon University Hospital, Dijon, France, Dijon, France
  • 2 CHU Dijon Bourgogne, INSERM, Université de Bourgogne, CIC 1432, Module Épidémiologie Clinique, Dijon, France, Dijon, France
  • 3 Service de Médecine Nucléaire, Centre Georges Francois Leclerc, 21000 Dijon, France, Dijon, France
  • 4 Institut de Chimie Moléculaire de l'Université de Bourgogne, ICMUB UMR CNRS 6302, Université de Bourgogne, 21000 Dijon, France, Dijon, France
  • 5 Department of Internal Medicine, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France, Lyon, France
  • 6 Department of Internal Medicine and Clinical Immunology, Dijon-Burgundy University Hospital, Dijon, France, Dijon, France
  • 7 Department of Vascular Medicine, Dijon University Hospital, Dijon, France, Dijon, France
  • 8 Université Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France, Dijon, Burgundy, France
  • 9 Department of Rheumatology, Dijon University Hospital, Dijon, France, Dijon, France

The final, formatted version of the article will be published soon.

    PET/CT is an imaging modality that is increasingly being used to diagnose large-vessel vasculitis. In the case of giant cell arteritis, it was first used to demonstrate inflammation of the walls of large arterial trunks such as the aorta and its main branches, showing that aortic involvement is common in this vasculitis and associated with the occurrence of aortic complications such as aneurysms. More recently, with the advent of digital PET/CT, study of the cranial arteries (i.e. temporal, occipital, maxillary and vertebral arteries) has become possible, further increasing the diagnostic interest of this examination for the diagnosis of GCA. Despite these advantages, there are still limitations and questions regarding the use of PET/CT for the diagnosis and especially the follow-up of GCA. The aim of this review is to take stock of currently available data on the use of PET/CT for GCA diagnosis and follow-up.

    Keywords: Giant Cell Arteritis, 18F-fluorodeoxyglucose positron emission tomography/computed tomography, diagnosis, Monitoring MS: AbbVie consulting, Argenx consulting, Boehringer Ingelheim consulting, GSK consulting, Novartis consulting and research grant

    Received: 24 Jul 2024; Accepted: 26 Sep 2024.

    Copyright: © 2024 THIBAULT, ALBERINI, BILLET, GREIGERT, RAMON, Devilliers, COCHET, Bonnotte and SAMSON. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Maxime SAMSON, Department of Internal Medicine and Systemic Disease, Dijon University Hospital, Dijon, France, Dijon, France

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.