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CASE REPORT article

Front. Med.
Sec. Dermatology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1468712

Cryptococcoid Sweet syndrome: case report

Provisionally accepted
Martina Volonté Martina Volonté 1Giacomo Fiandrino Giacomo Fiandrino 2Camilla Vassallo Camilla Vassallo 1Stefania Barruscotti Stefania Barruscotti 1,3Chiara Giorgini Chiara Giorgini 1Carlo F. Tomasini Carlo F. Tomasini 1,3Valeria Brazzelli Valeria Brazzelli 1,3*
  • 1 Dermatology Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Pavia, Lombardy, Italy
  • 2 San Matteo Hospital Foundation (IRCCS), Pavia, Lombardy, Italy
  • 3 Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy

The final, formatted version of the article will be published soon.

    Cryptococcoid Sweet syndrome (cSS) is a recently described clinical and histological variant of Sweet syndrome (SS). Its cutaneous presentation is similar to the classical form of SS but includes atypical findings and capsular- and yeast-like structures on microscopy reminiscent of Cryptococcus species. However, in cSS, fungal stainings and cultural examination are negative, whereas myeloperoxidase staining on biopsy specimens is typically positive. Due to the rarity and the diagnostic challenge represented by this disease, its extracutaneous involvement, and the latency in its diagnosis, this condition is frequently associated with poor prognosis. Herein, we report the case of a cSS patient with a positive outcome.

    Keywords: Acute febrile neutrophilic dermatosis, cryptococcoid acute febrile neutrophilic dermatosis, cryptococcoid Sweet syndrome, neutrophilic dermatosis, Sweet Syndrome

    Received: 22 Jul 2024; Accepted: 20 Sep 2024.

    Copyright: © 2024 Volonté, Fiandrino, Vassallo, Barruscotti, Giorgini, Tomasini and Brazzelli. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Valeria Brazzelli, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy

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