AUTHOR=Pan Shaorong , Yang Jiejin , Liu Zining , Nai Rile , Chen Zeyang TITLE=A prediction model to differentiate transient ischemia from irreversible transmural necrosis in closed-loop small bowel obstruction JOURNAL=Frontiers in Medicine VOLUME=11 YEAR=2024 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1466754 DOI=10.3389/fmed.2024.1466754 ISSN=2296-858X ABSTRACT=Introduction

The study aims to develop a prediction model to differentiate transient ischemia from irreversible transmural necrosis in closed-loop small bowel obstruction (CL-SBO).

Methods

A total of 180 participants with CL-SBO between January 2010 and December 2019, of which 122 had complete radiologic data, were included to investigate the significant clinical and imaging characteristics for differentiating patients with necrosis from transient ischemia. A logistic regression model was developed and validated.

Results

In a multivariate analysis, the American Society of Anesthesiologists physical status classification system >2 is the independent predictor for transmural necrosis. Another multivariate analysis, including clinical and imaging factors, revealed that the imaging sign of mesenteric vessel interruption was an independent risk factor for necrosis. The diagnostic model developed using these two factors has excellent performance among the validation sets, with an area under the curve of 0.89.

Conclusion

The diagnostic model and innovative imaging signs have substantial potential in solving this complex clinical problem.