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CASE REPORT article
Front. Med.
Sec. Nuclear Medicine
Volume 11 - 2024 |
doi: 10.3389/fmed.2024.1461749
Huge intermediate-grade myofibroblastic sarcoma in the retroperitoneum revealed by 18 F-FDG PET/CT: A case report
Provisionally accepted- 1 Affiliated Hospital of Zunyi Medical University, Zunyi, China
- 2 People’s Hospital of Qianxinan Buyi and Miao Minority Autonomous Prefecture, China, Xingyi, China
Myofibroblastic sarcoma (MS) is a relatively rare malignant bone and soft tissue tumor of myofibroblastic origin, with some characteristics of both smooth muscle cells and fibroblasts.MS can occur at any age and in different areas, especially the head and neck, but is rarely reported retroperitoneally. MS is usually a low-grade malignancy, while the number of moderate and highly malignant reports is rare. Herein, we describe an instance of intermediate-grade myofibroblastoma sarcoma (IGMS) originating from the retroperitoneum, supported by a pathological diagnosis. The 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission computed tomography (PET) /computed tomography (CT) scan revealed a large, borderless mass located retroperitoneally with significantly increased 18 F-FDG uptake, accompanied by adjacent visceral and soft tissue infiltration, and peripheral lymph node metastasis. The patient was treated with chemotherapy for three weeks, but the tumor did not shrink significantly, and the patient gave up treatment and died five months later. Through this case report, the diagnosis and treatment of moderate malignant retroperitoneal myofibroblastoma were discussed, so as to increase clinicians' understanding of the disease.
Keywords: myofibroblastic sarcoma, 18F-FDG, PET/CT, Computed tomography (CT), Retroperitoneal
Received: 09 Jul 2024; Accepted: 23 Aug 2024.
Copyright: © 2024 Li, Mei, Wang, Cai and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jiong Cai, Affiliated Hospital of Zunyi Medical University, Zunyi, China
Xianwen Hu, Affiliated Hospital of Zunyi Medical University, Zunyi, China
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