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ORIGINAL RESEARCH article

Front. Med.
Sec. Hematology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1456695

Association Between ABO Blood Groups and Hematological Myeloid Neoplasms in Adolescents and Adults

Provisionally accepted
Miao Zhou Miao Zhou 1*Tongyu Li Tongyu Li 1Yongcheng Sun Yongcheng Sun 1*Guifang Ouyang Guifang Ouyang 1*Wanchuan Zhuang Wanchuan Zhuang 2*Ping Zhang Ping Zhang 1*
  • 1 Ningbo First Hospital, Ningbo, China
  • 2 Second People's Hospital of Lianyungang, Lianyungang, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    Background: Prior research suggests a potential link between ABO blood types and susceptibility to various malignancies. The correlation between ABO blood types and hematological myeloid neoplasms, however, remains inadequately explored.Objective: This study investigates the association between ABO blood groups and the incidence of hematological myeloid neoplasms in adolescents and adults.In this retrospective clinical study, 1022 adolescent and adult cases of myeloid neoplasms diagnosed at our institution were initially considered. After excluding conditions potentially linked to ABO blood types from prior studies, 792 eligible cases were analyzed. These cases were categorized based on disease subtypes and compared with a control group for blood type distribution.Results: Our findings reveal a significantly higher prevalence of blood type A in patients with myeloid neoplasms compared to the control group, except for chronic myelocytic leukemia and myeloproliferative neoplasms. Conversely, the prevalence of blood type AB in myeloid neoplasms was notably lower than in the control group.The study suggests a potential association between ABO blood types and the risk of developing hematological myeloid neoplasms in adolescents and adults.Further research is warranted to elucidate the underlying mechanisms of this relationship.

    Keywords: ABO blood groups, Hematological Myeloid Neoplasms, adolescents, adults, Association

    Received: 29 Jun 2024; Accepted: 28 Aug 2024.

    Copyright: © 2024 Zhou, Li, Sun, Ouyang, Zhuang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Miao Zhou, Ningbo First Hospital, Ningbo, China
    Yongcheng Sun, Ningbo First Hospital, Ningbo, China
    Guifang Ouyang, Ningbo First Hospital, Ningbo, China
    Wanchuan Zhuang, Second People's Hospital of Lianyungang, Lianyungang, 222006, Jiangsu Province, China
    Ping Zhang, Ningbo First Hospital, Ningbo, China

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