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CASE REPORT article

Front. Med.
Sec. Gastroenterology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1456246

Treatment of Giant Fecalith Colonic Obstruction in a Patient with Duchenne Muscular Dystrophy using Endoscopic Injection of Hydrogen Peroxide: A Case Report and Literature Review

Provisionally accepted
Cheng Huang Cheng Huang Zhichao Gao Zhichao Gao Yuhang Zhang Yuhang Zhang Guofeng Li Guofeng Li *Lida Ge Lida Ge *
  • The First people's Hospital of Xiaoshan District, Hangzhou, China

The final, formatted version of the article will be published soon.

    Introduction: Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder primarily affecting cardiac and skeletal muscles, with gastrointestinal obstruction being an infrequent complication. Case report: We present a 17-year-old boy with DMD (G-to-T transversion at c.4150 in the gene encoding dystrophin protein) who developed severe colonic obstruction due to fecal impaction. Abdominal computed tomography revealed an obstructing fecalith in the left colon (length: 39.5 cm, width: 18.3 cm, height: 12.7 cm). Despite the application of initial conservative measures including fasting, enemas, and fluid resuscitation, the obstruction persisted. Therefore, we performed manual disimpaction and endoscopic injection of hydrogen peroxide, effectively alleviating the obstruction. Discussion: This case underscores the necessity of devising stage-specific, tailored strategies for the prevention and management of gastrointestinal complications in patients with DMD.

    Keywords: Duchenne muscular dystrophy, Fecalith, Colonic obstruction, conservative management, gastrointestinal complications

    Received: 28 Jun 2024; Accepted: 18 Nov 2024.

    Copyright: © 2024 Huang, Gao, Zhang, Li and Ge. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Guofeng Li, The First people's Hospital of Xiaoshan District, Hangzhou, China
    Lida Ge, The First people's Hospital of Xiaoshan District, Hangzhou, China

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