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SYSTEMATIC REVIEW article

Front. Med.
Sec. Gastroenterology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1452227
This article is part of the Research Topic Improving the Gut Microbiome: Applications of Fecal Transplantation in Disease - Volume II View all articles

Global Trends and Collaborative Networks in Gut Microbiota-Insulin Resistance Research: A Comprehensive Bibliometric Analysis (2000-2024)

Provisionally accepted
Gulshara Z. Abildinova Gulshara Z. Abildinova 1Valeriy V. Benberin Valeriy V. Benberin 1Tamara Vochshenkova Tamara Vochshenkova 1Alireza Afshar Alireza Afshar 2,3Nadiar M. Mussin Nadiar M. Mussin 4Asset Kaliyev Asset Kaliyev 4Zhussupova Zhanna Zhussupova Zhanna 5Amin Tamadon Amin Tamadon 3,6*
  • 1 Independent researcher, Astana, Kazakhstan
  • 2 Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Bushehr, Iran
  • 3 PerciaVista R&D Co., Shiraz, Iran
  • 4 West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan
  • 5 Department of Neurology, Psychiatry and Narcology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan
  • 6 Department of Natural Sciences, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan

The final, formatted version of the article will be published soon.

    Background: The human gut microbiota plays a crucial role in maintaining metabolic health, with substantial evidence linking its composition to insulin resistance. This study aims to analyze the global scholarly contributions on the relationship between intestinal microbiota and insulin resistance from 2000 to 2024. Methods: A bibliometric analysis was conducted using data from Scopus and Web of Science Core Collection. The search strategy included terms related to "Gastrointestinal Microbiome" and "Insulin Resistance" in the title or abstract. Results: The analysis of 1,884 relevant studies from 510 sources was conducted, revealing a mean citation of 51.36 per manuscript and a remarkable annual growth rate of 22.08%. The findings highlight the significant role of gut microbiota in insulin resistance, corroborating prior studies that emphasize its influence on metabolic disorders. The literature review of the current study showed key mechanisms include the regulation of short-chain fatty acids (SCFAs) and gut hormones, which are critical for glucose metabolism and inflammation regulation. The analysis also identifies "Food & Function" as the most productive journal and Nieuwdorp M. as a leading author, underscoring the collaborative nature of this research area. Conclusions: The consistent increase in publications in the field of gut microbiota and insulin resistance indicates growing recognition of the gut microbiota's therapeutic potential in treating insulin resistance and related metabolic disorders. Future research should focus on standardizing methodologies and conducting large-scale clinical trials to fully realize these therapeutic possibilities.

    Keywords: Gastrointestinal microbiome, Insulin Resistance, insulin sensitivity, Gut Microbiota, Short-chain fatly acids

    Received: 20 Jun 2024; Accepted: 01 Aug 2024.

    Copyright: © 2024 Abildinova, Benberin, Vochshenkova, Afshar, Mussin, Kaliyev, Zhanna and Tamadon. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Amin Tamadon, PerciaVista R&D Co., Shiraz, Iran

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